General interest is a pretty good concept for a physical product that gets delivered to your doorstep, where getting all those disparate sections bundled together makes sense. It’s not such a great concept on the web. The web hates artificial bundles. If you’re going to do a general-interest news product online, you have to be prepared to do it on the cheap, as Matt Drudge and Arianna Huffington do (or at least used to do, in the latter case). Conversely, if you want to put out an expensively produced, professionally-edited product, it’s better to stick to a niche, preferably one with a demographic that advertisers want to reach, like technology or business.
And a related piece:
Now Can We All Agree That The “High Quality Web Content” Experiment Has Failed? — http://techcrunch.com/2011/08/27/who-wouldve-thought-it-figures/